3-甲基-3-丁烯-1-醇合成路线 （共 220 条）
反应条件
1: [Ru(COD)(Cl2)]2; 1-n-butyl-3-methylimidazolium chloride; potassium tert-butylate; tri-cyclo-hexyl-phosphine / toluene / 12 h / |Reflux; |Inert atmosphere; |Schlenk technique 2: [Ru(COD)(Cl2)]2; 1-n-butyl-3-methylimidazolium chloride; potassium tert-butylate; tri-cyclo-hexyl-phosphine / toluene / 12 h / |Reflux; |Inert atmosphere; |Schlenk technique View Scheme
反应条件
1: [Ru(COD)(Cl2)]2; 1-n-butyl-3-methylimidazolium chloride; potassium tert-butylate; tri-cyclo-hexyl-phosphine / toluene / 12 h / |Reflux; |Inert atmosphere; |Schlenk technique 2: dcype; [Ru(Pn-Bu3)4H2] / toluene / 12 h / |Reflux; |Inert atmosphere; |Schlenk technique View Scheme
反应条件
hydrogen; RhH(CO)(triphenylphosphine)3; dicobalt octacarbonyl in 1,4-dioxane T=100°C; P=100 Torr; 12 h;
参考文献
Hirai, Kenji; Fujita, Makoto; Fuchikami, Takamasa
Journal of Organometallic Chemistry, 1985 , vol. 279, p. 203 - 214
反应条件
titanium tetrachloride
参考文献
Chemistry Letters, , p. 1819 - 1822
反应条件
Montmorillonite K 10 T=20°C; 216 h; Further byproducts given;
参考文献
Desaubry, Laurent; Nakatani, Yoichi; Ourisson, Guy
Tetrahedron Letters, 2003 , vol. 44, # 36 p. 6959 - 6961
反应条件
N-bromosuccinmide; triphenylphosphine in dichloromethane 3 h; Ambient temperature;
参考文献
Berkowitz, William F.; Wu, Yanzhong
Journal of Organic Chemistry, 1997 , vol. 62, # 5 p. 1536 - 1539
反应条件
1.1: 85 percent / pyridine / 16 h / 0 °C 2.1: 72 percent / NaI / acetone / 2 h / Heating 3.1: LDA / tetrahydrofuran; hexane 3.2: 62 percent / tetrahydrofuran; hexane 4.1: 74 percent / aq. AcOH / 2 h / 20 °C 5.1: 38 percent / Me2AlCl / hexane / 24 h / -78 - 20 °C View Scheme
参考文献
Braddock, D. Christopher; Brown, John M.
Collection of Czechoslovak Chemical Communications, 2000 , vol. 65, # 5 p. 741 - 756
反应条件
1: 88 percent Spectr. / N2O4 / aq. HNO3 / 50 °C / Heating 2: 4.9 g / 83 - 89 °C / 15 Torr / Heating View Scheme
参考文献
Wilkes, John B.; Wall, Robert G.
Journal of Organic Chemistry, 1980 , vol. 45, # 2 p. 247 - 250
反应条件
ozone - oxygen mixture; dimethylsulfide 1.) methanol, -78 deg C, 2.) -78 deg C -> room temperature; Yield given. Multistep reaction;
参考文献
Sueiras; Okamura
Journal of the American Chemical Society, 1980 , vol. 102, # 20 p. 6255 - 6259
反应条件
[Ru(COD)(Cl2)]2; potassium tert-butylate; 1-n-butyl-3-methylimidazolium chloride; tri-cyclo-hexyl-phosphine in toluene 12 h; RefluxInert atmosphereSchlenk technique;
参考文献
EP2597081 A1, ;
Paragraph 0124 ;
