3-溴-5-甲基-5H-呋喃-2-酮合成路线 （共 4 条）
反应条件
1: With bromine in tetrachloromethane
1.5 h; Heating;
2: With triethylamine
T=20°C; 2 h;
参考文献
Mathews, Christopher J.; Taylor, John; Tyte, Melloney J.; Worthington, Paul A.
Synlett, 2005 , # 3 art. no. D37404ST, p. 538 - 540
反应条件
1: With boron trifluoride diethyl etherate in dichloromethane
T=0°C;
2: With N-bromosuccinmide in dichloromethane
T=0 - 20°C; 0.666667 h;
3: With lithium carbonate; lithium chloride in N,N-dimethyl-formamide
T=70°C; 0.166667 h; Further stages.;
参考文献
Boukouvalas, John; Loach, Richard P.
Journal of Organic Chemistry, 2008 , vol. 73, # 20 p. 8109 - 8112
反应条件
1.1: 43 percent / Et3N / benzene / 15 h / Heating
2.1: Br2 / CCl4 / 3 h / Heating
2.2: 46 percent / Et3N / 4 h
View Scheme
参考文献
Sorg, Achim; Blank, Frederik; Bruckner, Reinhard
Synlett, 2005 , # 8 art. no. G10905ST, p. 1286 - 1290
反应条件
1.1: 60 percent / H3PO4 / Heating
2.1: 43 percent / Et3N / benzene / 15 h / Heating
3.1: Br2 / CCl4 / 3 h / Heating
3.2: 46 percent / Et3N / 4 h
View Scheme
参考文献
Sorg, Achim; Blank, Frederik; Bruckner, Reinhard
Synlett, 2005 , # 8 art. no. G10905ST, p. 1286 - 1290
