N-[(1,1-二甲基乙氧基)羰基]-N-(苯基甲基)-甘氨酸合成路线 （共 24 条）
反应条件
triethylamine in water T=25°C; 3 h;
参考文献
Journal of the American Chemical Society, , vol. 125, # 35 p. 10664 - 10671
反应条件
triethylamine in dichloromethane
参考文献
WO2008/76805 A2, ;
Page/Page column 127 ;
WO 2008/076805 A2
反应条件
sodium hydroxide in methanol 18 h; Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 39, # 7 p. 1472 - 1484
反应条件
sodium hydride in tetrahydrofuran
参考文献
Polish Journal of Chemistry, , vol. 68, # 5 p. 1047 - 1054
反应条件
sodium hydrogencarbonate in 1,4-dioxane; water; acetic acid
反应条件
hydrogenchloride; NaH in tetrahydrofuran
参考文献
US6057451 A1, ;
US 6057451 A
反应条件
triethylamine in 1,4-dioxane; water 3.5 h; Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 26, # 2 p. 167 - 174
反应条件
sodium hydride in tetrahydrofuran 24 h;
参考文献
Synthetic Communications, , vol. 24, # 17 p. 2429 - 2435
反应条件
hydrogen; palladium on activated charcoal in ethanol 18 h;
参考文献
Helvetica Chimica Acta, , vol. 77, # 4 p. 1124 - 1165
反应条件
1: 1N aq. NaOH / methanol / 0.25 h / Ambient temperature 2: H2 / 10percent Pd/C / methanol / 12 h / 2585.7 Torr 3: Et3N / H2O; dioxane / 2 h View Scheme
参考文献
Synthetic Communications, , vol. 24, # 17 p. 2429 - 2435
