1: 1.) hexamethylphosphotriamide; 2.) ammonium chloride / 1.) THF, -50 deg C, 4 h; 2.) water, -80 deg C 2: 1.) methyl iodide; 2.) triethylamine / 1.) overnight; 2.) toluene, 1 h, reflux, 12 h View Scheme