4-(4-溴苯基)-2-甲基-3-丁炔-2-醇合成路线 （共 7 条）
反应条件
1: copper(ll) bromide / nitromethane / 12 h / 20 °C / |Darkness 2: triethylamine; copper(l) iodide; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 12 h / 80 °C / |Inert atmosphere 3: chloroform / 2 h / |UV-irradiation View Scheme
参考文献
Gschneidtner, Tina A.; Moth-Poulsen, Kasper
Tetrahedron Letters, 2013 , vol. 54, # 40 p. 5426 - 5429
反应条件
1: copper(ll) bromide / nitromethane / 12 h / 20 °C / |Darkness 2: triethylamine; copper(l) iodide; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 12 h / 80 °C / |Inert atmosphere 3: potassium hydroxide / toluene / 12 h / 110 °C / |Inert atmosphere; |UV-irradiation View Scheme
参考文献
Gschneidtner, Tina A.; Moth-Poulsen, Kasper
Tetrahedron Letters, 2013 , vol. 54, # 40 p. 5426 - 5429
反应条件
potassium hydroxide in 1,4-dioxane T=120°C; 3 h;
参考文献
Lo, Chih-Nan; Hsu, Chain-Shu
Journal of Polymer Science, Part A: Polymer Chemistry, 2011 , vol. 49, # 15 p. 3355 - 3365
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; triphenylphosphine
T=65°C; 6 h;
参考文献
Li, Jie; Huang, Pengcheng
Beilstein Journal of Organic Chemistry, 2011 , vol. 7, p. 426 - 431
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine
Sonogashira Cross-Coupling; Inert atmosphereReflux;
参考文献
Smeyanov, Alexey; Schmidt, Andreas
Synthetic Communications, 2013 , vol. 43, # 20 p. 2809 - 2816
反应条件
in ethyl acetate
2 h; UV-irradiation;
参考文献
Gschneidtner, Tina A.; Moth-Poulsen, Kasper
Tetrahedron Letters, 2013 , vol. 54, # 40 p. 5426 - 5429
反应条件
in diethyl ether
1) r.t., 1.5 h, 2) reflux, 0.5 h;
参考文献
Mayr, Herbert; Halberstadt-Kausch, Inge K.
Chemische Berichte, 1982 , vol. 115, # 11 p. 3479 - 3515
