6,7-二羟基-2,2-二甲基-2,3-二氢-4H-苯并吡喃-4-酮合成路线 （共 5 条）
反应条件
potassium carbonate in acetone
参考文献
Alkaloida Vegyeszeti Gyar
Patent: US4866089 A1, 1989 ;
反应条件
1: 80 percent / K2CO3, KI / dimethylformamide / 2 h / 80 °C 2: 88 percent / K2CO3 / dimethylformamide / 15 h / 80 °C 3: 1.) NaBH4; 2.) 4 M HCl / 1.) methanol, 25 deg C, 2 h; 2.) THF, 25 deg C, 1.5 h View Scheme
参考文献
Timar, Tibor; Jaszberenyi, J. Csaba
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 871 - 877
反应条件
1: 78 percent / K2CO3, KI / dimethylformamide / 4 h / 80 °C
2: 87 percent / K2CO3 / dimethylformamide / 11 h / 80 °C
3: NaBH4 / methanol / 2 h / 50 °C
4: 4 M HCl / tetrahydrofuran / 3 h / 20 °C
View Scheme
参考文献
Timar, Tibor; Jaszberenyi, J. Csaba; Hosztafi, Sandor
Acta Chimica Hungarica, 1989 , vol. 126, # 2 p. 149 - 156
反应条件
1: 70 percent / K2CO3, KI / dimethylformamide / 4 h / 80 °C
2: 88 percent / K2CO3 / dimethylformamide / 7 h / 80 °C
3: NaBH4 / methanol / 1.5 h / 50 °C
4: 4 M HCl / tetrahydrofuran / 2 h / 20 °C
View Scheme
参考文献
Timar, Tibor; Jaszberenyi, J. Csaba; Hosztafi, Sandor
Acta Chimica Hungarica, 1989 , vol. 126, # 2 p. 149 - 156
反应条件
1: 80 percent / K2CO3, KI / dimethylformamide / 2 h / 80 °C
2: 88 percent / K2CO3 / dimethylformamide / 15 h / 80 °C
View Scheme
参考文献
Timar, Tibor; Jaszberenyi, J. Csaba
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 871 - 877
