1: With lithium; 4,4'-di-tert-butylbiphenyl in tetrahydrofuran T=-78°C; 3 h; 2: With water in tetrahydrofuran T=-78°C; 0.333333 h; 3: With water in tetrahydrofuran T=-78 - 20°C; Further stages.;

1.1: N-bromosuccinimide; AIBN 2.1: tetrabutylammonium hydroxide / dioxane 3.1: palladium 4.1: Li; DTBB / tetrahydrofuran / 3 h / -78 °C 5.1: H2O / 0.5 h / -78 °C 5.2: H2O / -78 - 20 °C View Scheme

1.1: tetrabutylammonium hydroxide / dioxane 2.1: palladium 3.1: Li; DTBB / tetrahydrofuran / 3 h / -78 °C 4.1: H2O / 0.5 h / -78 °C 4.2: H2O / -78 - 20 °C View Scheme

Sodium bromate; sodium hydrogen sulphate monohydrate in acetonitrile 1.5 h; Reflux;