sodium hydroxide 24 h; Ambient temperature;

sodium hydroxide in water Ambient temperature;

1: 45 percent / methanol; H2O / 8 h / 70 °C 2: 99.3 percent / NH4Cl / aq. NH3 / 50 h / 37 °C / enzymatic hydrolysis with Pseudomonas putida at pH 9 3: 1.) NaNO2, 2N H2SO4; 2.) KBr, NaNO2, 3N H2SO4 / 1.) 50percent CH3COOH, r.t., 24 h; 2.) 50percent CH3COOH, 0-5 deg C, 1 h 4: 95 percent / SOCl2 / 24 h / Ambient temperature 5: 74 percent / (NH4)2CO3 / nitromethane; H2O / 96 h / 50 °C 6: 85 percent / TFA / 3 h / Ambient temperature 7: 75 percent / 1N NaOH / 24 h / Ambient temperature View Scheme

1: 99.3 percent / NH4Cl / aq. NH3 / 50 h / 37 °C / enzymatic hydrolysis with Pseudomonas putida at pH 9 2: 1.) NaNO2, 2N H2SO4; 2.) KBr, NaNO2, 3N H2SO4 / 1.) 50percent CH3COOH, r.t., 24 h; 2.) 50percent CH3COOH, 0-5 deg C, 1 h 3: 95 percent / SOCl2 / 24 h / Ambient temperature 4: 74 percent / (NH4)2CO3 / nitromethane; H2O / 96 h / 50 °C 5: 85 percent / TFA / 3 h / Ambient temperature 6: 75 percent / 1N NaOH / 24 h / Ambient temperature View Scheme

1: 95 percent / SOCl2 / 24 h / Ambient temperature 2: 74 percent / (NH4)2CO3 / nitromethane; H2O / 96 h / 50 °C 3: 85 percent / TFA / 3 h / Ambient temperature 4: 75 percent / 1N NaOH / 24 h / Ambient temperature View Scheme

1: 74 percent / (NH4)2CO3 / nitromethane; H2O / 96 h / 50 °C 2: 85 percent / TFA / 3 h / Ambient temperature 3: 75 percent / 1N NaOH / 24 h / Ambient temperature View Scheme

1: 1.) NaNO2, 2N H2SO4; 2.) KBr, NaNO2, 3N H2SO4 / 1.) 50percent CH3COOH, r.t., 24 h; 2.) 50percent CH3COOH, 0-5 deg C, 1 h 2: 95 percent / SOCl2 / 24 h / Ambient temperature 3: 74 percent / (NH4)2CO3 / nitromethane; H2O / 96 h / 50 °C 4: 85 percent / TFA / 3 h / Ambient temperature 5: 75 percent / 1N NaOH / 24 h / Ambient temperature View Scheme

1: in water; ethyl acetate T=19 - 20°C; pH=10 - 11; 5 h; 2: T=30°C; pH=4.3 - 4.7; 0.166667 h;

water T=40°C; 13149 h;

sodium hydroxide; trifluoroacetic acid Multistep reaction;