1: 56 percent / acetate buffer / methanol; H2O / 95 h / Ambient temperature; pH 5 2: 83 percent / 50percent NaH / dimethylformamide / Ambient temperature 3: 37 percent / K2CO3 / dimethylsulfoxide / 3 h / 30 °C 4: 96 percent / H2 / 10percent Pd/C / acetic acid / 6 h / 760 Torr / Ambient temperature View Scheme