(1R,4R)-双环[2.2.2]辛烷-2,5-二酮合成路线 (共 6 条)
反应条件
hydrogen; platinum(IV) oxide in ethanol
P=775.7 Torr; 0.5 h;
参考文献
Hill, Richard K.; Morton, Gerald H.; Peterson, John R.; Walsh, James A.; Paquette, Leo A.
Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5528 - 5533
反应条件
1: 12 percent / sodium acetate; AcOH / ethanol / 3 h / Heating
2: 4.5 percent / aq. H2SO4 / 4 h / Heating
View Scheme
参考文献
Tokunaga, Norihito; Otomaru, Yusuke; Okamoto, Kazuhiro; Ueyama, Kazuhito; Shintani, Ryo; Hayashi, Tamio
Journal of the American Chemical Society, 2004 , vol. 126, # 42 p. 13584 - 13585
反应条件
1: 46.9 g / 6 h / 190 °C
2: 95 percent / water / Heating
3: 30 percent / lead tetraacetate, pyridine / dioxane / 0.17 h / 60 °C
4: p-toluenesulfonic acid monohydrate / xylene / 81 h / Heating
5: Heating
6: 100 percent / H2 / PtO2 / ethanol / 0.5 h / 775.7 Torr
View Scheme
参考文献
Hill, Richard K.; Morton, Gerald H.; Peterson, John R.; Walsh, James A.; Paquette, Leo A.
Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5528 - 5533
反应条件
1: Heating
2: 100 percent / H2 / PtO2 / ethanol / 0.5 h / 775.7 Torr
View Scheme
参考文献
Hill, Richard K.; Morton, Gerald H.; Peterson, John R.; Walsh, James A.; Paquette, Leo A.
Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5528 - 5533
反应条件
Candida rugosa lipase
pH=7.5; 2 h; aq. phosphate buffer;
参考文献
Luo, Yunfei; Carnell, Andrew J.
Journal of Organic Chemistry, 2010 , vol. 75, # 6 p. 2057 - 2060
反应条件
1: With sodium acetate; acetic acid in ethanol
3 h; Heating;
2: With sulfuric acid in water
4 h; Heating;
参考文献
Otomaru, Yusuke; Okamoto, Kazuhiro; Shintani, Ryo; Hayashi, Tamio
Journal of Organic Chemistry, 2005 , vol. 70, # 7 p. 2503 - 2508