反应条件
1.1: pyridine / ethyl acetate / 21.25 h / 0 - 22 °C / |Inert atmosphere; |Large scale
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.67 h / -70 °C / |Inert atmosphere; |Large scale
2.2: 0.75 h / -70 - 0 °C / |Inert atmosphere; |Large scale
2.3: 1.67 h / 0 - 25 °C / |Inert atmosphere; |Large scale
View Scheme
参考文献
Denni-Dischert, Donatienne; Marterer, Wolfgang; Baenziger, Markus; Yusuff, Naeem; Batt, David; Ramsey, Tim; Geng, Peng; Michael, Walter; Wang, Run-Ming B.; Taplin Jr., Francis; Versace, Richard; Cesarz, David; Perez, Lawrence B.
Organic Process Research and Development, 2006 , vol. 10, # 1 p. 70 - 77
