6-氯-2H-1,4-苯并噁嗪-3(4H)-酮合成路线 （共 31 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide 1 h; Heating;
参考文献
Zuo, Hua; Meng, Lijuan; Ghate, Manjunath; Hwang, Kyu-Hyeon; Kweon Cho, Yong; Chandrasekhar; Raji Reddy; Shin, Dong-Soo
Tetrahedron Letters, 2008 , vol. 49, # 23 p. 3827 - 3830
反应条件
sodium hydrogencarbonate in dichloromethane; water
参考文献
Zeneca Limited
Patent: US5830890 A1, 1998 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide T=80°C; 0.25 h; microwave irradiation;
参考文献
Caliendo, Giuseppe; Perissutti, Elisa; Santagada, Vincenzo; Fiorino, Ferdinando; Severino, Beatrice; Cirillo, Donatella; D'Emmanuele Di Villa Bianca, Roberta; Lippolis, Laura; Pinto, Aldo; Sorrentino, Raffaella
European Journal of Medicinal Chemistry, 2004 , vol. 39, # 10 p. 815 - 826
反应条件
1: NaBH4 / 10percent Pd-C / methanol; H2O / 0.25 h 2: Zn / acetic acid View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 31, # 11 p. 3891 - 3896
反应条件
iron; acetic acid 2.5 h; Inert atmosphereReflux;
参考文献
Ramesh, Chintakunta; Raju, B. Rama; Kavala, Veerababurao; Kuo, Chun-Wei; Yao, Ching-Fa
Tetrahedron, 2011 , vol. 67, # 6 p. 1187 - 1192
反应条件
sodium hydrogencarbonate; N-benzyl-N,N,N-triethylammonium chloride in chloroform 1.) 1 h, 0-5 deg C, 2.) 5 h, 55 deg C;
参考文献
Huang; Chan
Synthesis, 1984 , vol. NO. 10, p. 851 - 852
反应条件
triethylamine in methanol T=110°C; 6 h;
参考文献
Hogale; Tarapure; Shelar; Jagdale
Journal of the Indian Chemical Society, 1985 , vol. 62, # 6 p. 471 - 472
反应条件
copper(l) iodide; 1,10-phenanthroline; caesium carbonate in 1,4-dioxane T=90°C; 24 h; Inert atmosphere;
参考文献
Chen, Dingben; Shen, Guodong; Bao, Weiliang
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 19 p. 4067 - 4073
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene; [C8mim][BF4] T=20°C; 2 h; chemoselective reaction;
参考文献
Sharifi, Ali; Barazandeh, Mehdi; Saeed Abaee; Mirzaei, Mojtaba
Tetrahedron Letters, 2010 , vol. 51, # 14 p. 1852 - 1855
反应条件
1: sodium hydrogen carbonate / CHCl3 / 0.2 h / 40 °C / microwave irradiation 2: 92 percent / potassium carbonate / dimethylformamide / 0.25 h / 80 °C / microwave irradiation View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 39, # 10 p. 815 - 826
