反应条件
1: 1.) diphenyl phosphoryl azide, Et3N / 1.) C6H6, reflux, 1.25 h, 2.) C6H6, reflux, 2 h
2: 1.) NaH / 1.) DMF, RT, 30 min, 2.) DMF, RT, 1 h
3: 89 percent / H2 / 10percent Pd/C / ethyl acetate
4: 39 percent / diphenyl ether / 2.75 h / 230 - 255 °C
5: 52 percent / DDQ / benzene / 2 h / Heating
View Scheme
参考文献
Kamikawa, Tadao; Hanaoka, Yasuyuki; Fujie, Satoru; Saito, Ken; Yamagiwa, Yoshiro; Fukuhara, Katsuya; Kubo, Isao
Bioorganic and Medicinal Chemistry, 1996 , vol. 4, # 8 p. 1317 - 1320
