2-[乙基-(2,4,6-三甲基苯基)氨基]-9,10-二甲氧基-6,7-二氢嘧啶并[6,1-a]异喹啉-4-酮合成路线 （共 6 条）
反应条件
potassium carbonate in acetone
Heating;
参考文献
Lal; Dohadwalla; Dadkar; D'Sa; de Souza
Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1470 - 1480
反应条件
1: 75 percent / EtONa / ethanol / 16 h / Heating
2: 100 percent / POCl3 / 2.5 h / 100 - 110 °C
3: 74 percent / CHCl3 / 20 h / Heating
4: 48 percent / K2CO3 / acetone / Heating
View Scheme
参考文献
Lal; Dohadwalla; Dadkar; D'Sa; de Souza
Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1470 - 1480
反应条件
1: 87 percent / EtONa / ethanol / 8 h / Heating
2: 87 percent / POCl3 / 4 h / 110 °C
3: 74 percent / CHCl3 / 20 h / Heating
4: 48 percent / K2CO3 / acetone / Heating
View Scheme
参考文献
Lal; Dohadwalla; Dadkar; D'Sa; de Souza
Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1470 - 1480
反应条件
1: 74 percent / CHCl3 / 20 h / Heating
2: 48 percent / K2CO3 / acetone / Heating
View Scheme
参考文献
Lal; Dohadwalla; Dadkar; D'Sa; de Souza
Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1470 - 1480
反应条件
1: 100 percent / POCl3 / 2.5 h / 100 - 110 °C
2: 74 percent / CHCl3 / 20 h / Heating
3: 48 percent / K2CO3 / acetone / Heating
View Scheme
参考文献
Lal; Dohadwalla; Dadkar; D'Sa; de Souza
Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1470 - 1480
反应条件
1: 87 percent / POCl3 / 4 h / 110 °C
2: 74 percent / CHCl3 / 20 h / Heating
3: 48 percent / K2CO3 / acetone / Heating
View Scheme
参考文献
Lal; Dohadwalla; Dadkar; D'Sa; de Souza
Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1470 - 1480
