2-氨基-3-溴-5-氯吡嗪合成路线 （共 3 条）
反应条件
pyridine; bromine in chloroform 0.5 h; Ambient temperature;
参考文献
Bradbury, Robert H.; Bath, Colin; Butlin, Roger J.; Dennis, Michael; Heys, Christine; Hunt, Sarah J.; James, Roger; Mortlock, Andrew A.; Sumner, Neil F.; Tang, Eric K.; Telford, Berwick; Whiting, Elaine; Wilson, Campbell
Journal of Medicinal Chemistry, 1997 , vol. 40, # 6 p. 996 - 1004
反应条件
in methanol 6 h; Heating;
参考文献
Bradbury, Robert H.; Bath, Colin; Butlin, Roger J.; Dennis, Michael; Heys, Christine; Hunt, Sarah J.; James, Roger; Mortlock, Andrew A.; Sumner, Neil F.; Tang, Eric K.; Telford, Berwick; Whiting, Elaine; Wilson, Campbell
Journal of Medicinal Chemistry, 1997 , vol. 40, # 6 p. 996 - 1004
反应条件
hydrogen bromide
1.) reflux, 30 min, 2.) reflux, 20 h; Yield given. Multistep reaction;
参考文献
Lumma Jr.; Randall; Cresson; Huff; Hartman; Lyon
Journal of Medicinal Chemistry, 1983 , vol. 26, # 3 p. 357 - 363
