1: 91 percent / pyridine / 2 h / 18 °C 2: 1.) NaH, 2.) NH3 / 1.) Me2NCHO, 18 deg C, 1 h; 2.) MeOH, 0 deg C, 19 h 3: H(1+) or OH(1-) View Scheme

1: 61 percent / 1 M NaOEt / ethanol / 24 h / 30 °C 2: 52 percent / K2CO3 / dimethylformamide / 30 °C 3: 0.1 M aq. HCl / 25 °C / var. of reagent, temp. View Scheme

1: 61 percent / 1 M NaOEt / ethanol / 24 h / 30 °C 2: 52 percent / K2CO3 / dimethylformamide / 30 °C View Scheme