反应条件
1: 1.) butyl lithium, 2,2,6,6-tetramethylpiperidine / 1.) hexane/THF, 0 deg C, 10 min, 2.) 30 min 2: 1.) sodium amide / 1.) toluene, reflux, 2 h, 2.) THF, 2 h 3: 84 percent / lithium aluminium hydride / tetrahydrofuran / 2 h / Heating 4: 92 percent / 12 M hydrochloric acid / 48 h / Heating View Scheme
参考文献
Bradley; Cavalla; Edington; et al.
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 4 p. 375 - 385
