反应条件
1: 1-methyl-azacycloheptan-2-one With 2,2,6,6-tetramethyl-piperidine; n-butyllithium in tetrahydrofuran; hexane
T=0°C; 0.333333 h;
2: 2-chloro-anisole in tetrahydrofuran; hexane
0.5 h;
参考文献
DeSolms, S. Jane; Ciccarone, Terrence M.; MacTough, Suzanne C.; Shaw, Anthony W.; Buser, Carolyn A.; Ellis-Hutchings, Michelle; Fernandes, Christine; Hamilton, Kelly A.; Huber, Hans E.; Kohl, Nancy E.; Lobell, Robert B.; Robinson, Ronald G.; Tsou, Nancy N.; Walsh, Eileen S.; Graham, Samuel L.; Beese, Lorena S.; Taylor, Jeffrey S.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 14 p. 2973 - 2984
