5,8-二甲基呋喃并[2,3-h]苯并吡喃-2-酮合成路线 (共 5 条)
反应条件
potassium hydroxide in ethanol
1.33333 h; Heating;
参考文献
Guiotto; Rodighiero; Pastorini; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 6 p. 489 - 494
反应条件
1: 56 percent / conc. H2SO4 / Heating
2: 75 percent / K2CO3 / acetone / 5 h / Heating
3: 68.1 percent / N,N-diethylaniline / 5 h / Heating
4: 80.3 percent / AcONa / 1 h / Heating
5: 71.5 percent / bromine / acetic acid / 1 h / Ambient temperature
6: 44.5 percent / 4 percent KOH / ethanol / 1.33 h / Heating
View Scheme
参考文献
Guiotto; Rodighiero; Pastorini; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 6 p. 489 - 494
反应条件
1: 80.3 percent / AcONa / 1 h / Heating
2: 71.5 percent / bromine / acetic acid / 1 h / Ambient temperature
3: 44.5 percent / 4 percent KOH / ethanol / 1.33 h / Heating
View Scheme
参考文献
Guiotto; Rodighiero; Pastorini; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 6 p. 489 - 494
反应条件
1: 68.1 percent / N,N-diethylaniline / 5 h / Heating
2: 80.3 percent / AcONa / 1 h / Heating
3: 71.5 percent / bromine / acetic acid / 1 h / Ambient temperature
4: 44.5 percent / 4 percent KOH / ethanol / 1.33 h / Heating
View Scheme
参考文献
Guiotto; Rodighiero; Pastorini; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 6 p. 489 - 494
反应条件
1: 71.5 percent / bromine / acetic acid / 1 h / Ambient temperature
2: 44.5 percent / 4 percent KOH / ethanol / 1.33 h / Heating
View Scheme
参考文献
Guiotto; Rodighiero; Pastorini; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 6 p. 489 - 494