1-(4-氯苯基)-2-吡咯烷酮合成路线 (共 5 条)
反应条件
copper(l) iodide; cesium fluoride; N-methyl-2-(methylamino)ethylamine in ethyl acetate T=25°C; 18 - 24 h; Inert atmosphere;
参考文献
Phillips, Dean P.; Zhu, Xue-Feng; Lau, Thomas L.; He, Xiaohui; Yang, Kunyong; Liu, Hong
Tetrahedron Letters, 2009 , vol. 50, # 52 p. 7293 - 7296
反应条件
2: methanol; sodium methylate View Scheme
参考文献
Journal of the American Chemical Society, , vol. 77, p. 5420
反应条件
N-chloro-succinimide; acetic acid; palladium diacetate T=100°C; 12 h;
参考文献
Kalyani, Dipannita; Dick, Allison R.; Anani, Waseem Q.; Sanford, Melanie S.
Tetrahedron, 2006 , vol. 62, # 49 p. 11483 - 11498
反应条件
copper(l) iodide; (E)-1-(2-hydroxyphenyl)-3-(N,N-dimethylamino)prop-2-en-1-one; caesium carbonate; potassium iodide in acetonitrile T=82°C; Goldberg type reaction; 12 h; Inert atmosphere;
参考文献
Cheng, Cungui; Sun, Gonglei; Wan, Jieping; Sun, Cuirong
Synlett, 2009 , # 16 p. 2663 - 2668
反应条件
methanol; sodium methylate
参考文献
Journal of the American Chemical Society, , vol. 77, p. 5420