4-氯-2-硝基-1-丙-2-基苯合成路线 （共 4 条）
反应条件
1: With hydrogenchloride; sodium nitrite in water
T=0°C; 1.5 h;
2: With copper(l) chloride in water
T=20 - 80°C; 2 h;
参考文献
NERVIANO MEDICAL SCIENCES S.R.L.; BRASCA, Maria Gabriella; BANDIERA, Tiziano; BERTRAND, Jay Aaron; GNOCCHI, Paola; MIRIZZI, Danilo; NESI, Marcella; PANZERI, Achille
Patent: WO2012/143248 A1, 2012 ;
Location in patent: Page/Page column 25 ;
反应条件
nitric acid in sulfuric acid
T=25°C;
参考文献
Manglik, Ajay K.; Moodie, Roy B.; Schofield, Kenneth; Tobin, Geoffrey D.; Coombes, Robert G.; Hadjigeorgiu, Panicos
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 1606 - 1616
反应条件
2: 12.5 percent / HNO3 / aq. H2SO4 / 25 °C
View Scheme
参考文献
Manglik, Ajay K.; Moodie, Roy B.; Schofield, Kenneth; Tobin, Geoffrey D.; Coombes, Robert G.; Hadjigeorgiu, Panicos
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 1606 - 1616
反应条件
nitric acid; 4-aminobenzenesulfonic acid in sulfuric acid
T=25°C; various concentrations and molar ratios of HNO3 and H2SO4; Product distributionRate constant;
参考文献
Manglik, Ajay K.; Moodie, Roy B.; Schofield, Kenneth; Tobin, Geoffrey D.; Coombes, Robert G.; Hadjigeorgiu, Panicos
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 1606 - 1616
