反应条件
1: DIBAL / toluene / 1 h / -78 °C 2: 91.1 percent / TsCl, pyridine / 12 h / 35 °C 3: 1.) O3, 2.) NaBH4 / 1.) MeOH, -20 deg C, 2.) MeOH, from -20 deg C to RT 4: 98.6 percent / pyridine 5: 37 percent / H2O, tween 80, 0.1M phosphate buffer / CH2Cl2 / 24 h / 30 °C / lipase PS-30 (Amano) 6: TsCl, pyridine View Scheme
参考文献
Tanimoto, Hisahide; Oritani, Takayuki
Tetrahedron Asymmetry, 1996 , vol. 7, # 6 p. 1695 - 1704
