1: 1) (COCl)2/DMSO, 2) Et3N / 1) 1) CH2Cl2, -78 deg C, 30 min, 2) r.t., 1 h 2: tetrahydrofuran / 2 h / 0 °C 3: formic acid, Et3N / Pd2(dba)3CHCl3-P(OMe)3 / dioxane / 2 h / Ambient temperature; var. phosphorus ligands; var. times; var. concentrations of formic acid 4: 83 percent / H2 / 5percent Pd/C / methanol / 24 h / Ambient temperature 5: 11 percent / p-TsOH / tetrahydrofuran; H2O / 5 h / 50 °C View Scheme