2-氨基-4,6-二甲基嘧啶合成路线 （共 46 条）
反应条件
1: sodium hydrogencarbonate / ethanol; H2O / 48 h / Heating
2: N-bromosuccinimide (NBS) / CHCl3 / 12 h / Heating
View Scheme
参考文献
Rival; Grassy; Michel
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 5 p. 1170 - 1176
反应条件
in 1,4-dioxane; diethyl ether
T=20°C; 1 h;
参考文献
Reddy, K. Uma Maheswar; Reddy, A. Panasa; Reddy, B. Jayachandra
Asian Journal of Chemistry, 2013 , vol. 25, # 3 p. 1695 - 1697
反应条件
sodium hydrogencarbonate in dichloromethane
6 h; Heating;
参考文献
Ohkata, Katsuo; Ohsugi, Minoru; Yamamoto, Kazuhiro; Ohsawa, Mika; Akiba, Kin-Ya
Journal of the American Chemical Society, 1996 , vol. 118, # 27 p. 6355 - 6369
反应条件
sodium methylate; acetic acid in dimethylcarbamate; hexane
参考文献
E. I. Du Pont de Nemours and Company
Patent: US4435206 A1, 1984 ;
参考文献
Asplin et al.
Pr.roy.Soc.<B>, 1952 , vol. 139, p. 358,364
反应条件
sodium acetate in acetone
2 h; Heating;
参考文献
Yang, Guangfu; Xu, Li; Lu, Aihong
Heteroatom Chemistry, 2001 , vol. 12, # 6 p. 491 - 496
