4-氨基-6-羟基-2-甲基嘧啶合成路线 （共 15 条）
反应条件
1: With trichlorophosphate T=80°C; 1 h; 2: With N,N-dimethyl-formamide T=105°C; 3 h;
参考文献
Astrazeneca AB
Patent: US2009/23719 A1, 2009 ;
Location in patent: Page/Page column 21 ;
US 20090023719 A1
反应条件
ammonia; trichlorophosphate in water
参考文献
L'Oreal
Patent: US5438058 A1, 1995 ;
反应条件
2: aqueous Na2S2O4
View Scheme
参考文献
Craveri; Zoni
Chimica, 1957 , vol. 33, p. 473,475
反应条件
2: aqueous Na2S2O4
4: N,N-diethyl-aniline; POCl3
View Scheme
参考文献
Craveri; Zoni
Chimica, 1957 , vol. 33, p. 473,475
反应条件
sodium hydroxide; (NH4)2S2O8
T=0 - 20°C;
参考文献
Hurst, Derek T.
Australian Journal of Chemistry, 1983 , vol. 36, # 6 p. 1285 - 1289
