3,4-二氢-2H-苯并吡喃-3-甲醇合成路线 （共 10 条）
反应条件
lithium aluminium tetrahydride in diethyl ether 4 h;
参考文献
Mouysset, Genevieve; Payard, Marc; Grassy, Gerard; Tronche, Pierre; Dabire, Hubert; et al.
European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 539 - 544
反应条件
1: 94 percent / 10 percent NaOH / 5 h / Heating 2: 90 percent / hydrogen / 10 percent Pd/C / ethanol / 2 h / Ambient temperature 3: 66 percent / LiAlH4 / diethyl ether / 4 h View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 22, p. 539 - 544
反应条件
1: 90 percent / hydrogen / 10 percent Pd/C / ethanol / 2 h / Ambient temperature 2: 66 percent / LiAlH4 / diethyl ether / 4 h View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 22, p. 539 - 544
反应条件
1: 60 percent / 1,4-diazabicyclo<2.2.2>octane 2: 94 percent / 10 percent NaOH / 5 h / Heating 3: 90 percent / hydrogen / 10 percent Pd/C / ethanol / 2 h / Ambient temperature 4: 66 percent / LiAlH4 / diethyl ether / 4 h View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 22, p. 539 - 544
反应条件
palladium 10 on activated carbon; hydrogen in ethanol
参考文献
Brenna, Elisabetta; Gatti, Francesco G.; Malpezzi, Luciana; Monti, Daniela; Parmeggiani, Fabio; Sacchetti, Alessandro
Journal of Organic Chemistry, 2013 , vol. 78, # 10 p. 4811 - 4822
反应条件
(η5-ethyltetramethylcyclopentadienyl)(η6-benzene)rhodium(III) hexafluorophosphate 1.) acetone, nitromethane, 80 deg C, 4 d, 2.) dimethyl sulphoxide, 1 h, heating; Yield given. Multistep reaction;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 925 - 931
反应条件
1: 62 percent / sodium ethoxide / ethanol / Heating 2: 42 percent / lithium aluminium hydride / diethyl ether 3: 1.) (η5-ethyltetramethylcyclopentadienyl)(η6-benzene)rhodium(III) hexafluorophosphate / 1.) acetone, nitromethane, 80 deg C, 4 d, 2.) dimethyl sulphoxide, 1 h, heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 925 - 931
反应条件
1: 42 percent / lithium aluminium hydride / diethyl ether 2: 1.) (η5-ethyltetramethylcyclopentadienyl)(η6-benzene)rhodium(III) hexafluorophosphate / 1.) acetone, nitromethane, 80 deg C, 4 d, 2.) dimethyl sulphoxide, 1 h, heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 925 - 931
反应条件
1: sodium tetrahydroborate / methanol 2: palladium 10 on activated carbon; hydrogen / ethanol View Scheme
参考文献
Journal of Organic Chemistry, , vol. 78, # 10 p. 4811 - 4822
反应条件
thionyl chloride in chloroform 10 h; Ambient temperature;
参考文献
Mouysset, Genevieve; Payard, Marc; Grassy, Gerard; Tronche, Pierre; Dabire, Hubert; et al.
European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 539 - 544
