三甲基氰硅烷合成路线

参考文献

Ushakov, Dmitry B.; Gilmore, Kerry; Kopetzki, Daniel; McQuade, D. Tyler; Seeberger, Peter H.
Angewandte Chemie - International Edition, 2014 , vol. 53, # 2 p. 557 - 561
Angew. Chem., 2014 , vol. 126, # 2 p. 568 - 572,5

7677-24-9三甲基氰硅烷+

120-92-3环戊酮

49830-37-71-氨基环戊烷甲腈

参考文献

Jung, Michael E.; Ouk, Samedy; Yoo, Dongwon; Sawyers, Charles L.; Chen, Charlie; Tran, Chris; Wongvipat, John
Journal of Medicinal Chemistry, 2010 , vol. 53, # 7 p. 2779 - 2796

1632-76-43-甲基哒嗪+

7677-24-9三甲基氰硅烷+

6674-22-21,8-二氮杂双环[5.4.0]十一碳-7-烯+

98-59-9对甲苯磺酰氯

49840-90-66-甲基吡嗪-3-甲腈

参考文献

Eli Lilly and Company
Patent: US5707966 A1, 1998 ;
US 5707966 A

1072-72-6四氢噻喃-4-酮+

7677-24-9三甲基氰硅烷

50289-20-84-氨基四氢-2H-噻喃-4-甲腈

参考文献

MERCK SHARP and DOHME CORP.; ALTMAN, Michael, D.; BIENSTOCK, Corey, E.; BUTCHER, John, W.; CHILDERS, Kaleen Konrad; DI FRANCESCO, Maria Emilia; DONOFRIO, Anthony; ELLIS, John Michael; FISCHER, Christian; HAIDLE, Andrew, M.; JEWELL, James, P.; KNOWLES, Sandra Lee; NORTHRUP, Alan, B.; OTTE, Ryan, D.; PETERSON, Scott, L.; SMITH, Graham Frank
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Location in patent: Paragraph 00282 ;

7677-24-9三甲基氰硅烷+

122-78-1苯乙醛

50353-47-42-羟基3-苯基丙腈

参考文献

Kurz, Thomas; Widyan, Khalid
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 14 p. 2023 - 2027

502-49-8环辛酮+

7677-24-9三甲基氰硅烷

50361-50-71-三甲基甲硅烷基氧基-1-环辛烷甲腈

参考文献

Ohta; Yamashita; Arita; Kajiura; Kawasaki; Noda; Izumi
Chemical and Pharmaceutical Bulletin, 1995 , vol. 43, # 8 p. 1294 - 1301

7677-24-9三甲基氰硅烷+

529-34-01-四氢萘酮

50361-53-0

参考文献

Park, Boyoung Y.; Ryu, Ka Yeon; Park, Jung Hwan; Lee, Sang-Gi
Green Chemistry, 2009 , vol. 11, # 7 p. 946 - 948

参考文献

Kaur, Harpinder; Kaur, Gurmeet; Trehan, Sanjay
Synthetic Communications, 1996 , vol. 26, # 10 p. 1925 - 1929

7677-24-9三甲基氰硅烷+

529-34-01-四氢萘酮

50361-60-91-氨基甲基-1,2,3,4-四氢-萘-1-醇

参考文献

Campbell, Malcolm M.; Abbas, Nabeeha; Sainsbury, Malcolm
Tetrahedron, 1985 , vol. 41, # 23 p. 5637 - 5644

7677-24-9三甲基氰硅烷+

677-22-5叔丁基氯化镁

5037-65-0

参考文献

Mai, Khuong; Patil, Ghanshyam
Journal of Organic Chemistry, 1986 , vol. 51, # 18 p. 3545 - 3548