三甲基氰硅烷合成路线

参考文献

Day, Jonathan P.; Lindsay, Barbara; Riddell, Tracy; Jiang, Zhong; Allcock, Robert W.; Abraham, Achamma; Sookup, Sebastian; Christian, Frank; Bogum, Jana; Martin, Elisabeth K.; Rae, Robert L.; Anthony, Diana; Rosair, Georgina M.; Houslay, Daniel M.; Huston, Elaine; Baillie, George S.; Klussmann, Enno; Houslay, Miles D.; Adams, David R.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 9 p. 3331 - 3347

6635-88-7(1-氧基-吡啶-3-基)-乙腈+

7677-24-9三甲基氰硅烷+

79-44-7二甲氨基甲酰氯

5912-34-5

参考文献

Novartis AG
Patent: US6136821 A1, 2000 ;
US 6136821 A

4833-24-32-乙基吡啶 1-氧化物+

7677-24-9三甲基氰硅烷

59146-66-6

参考文献

Takeda Chemical Industries, Ltd.
Patent: EP1424336 A1, 2004 ;
Location in patent: Page 108 ;

22710-07-22,３－二甲基－吡啶氮氧化物+

7677-24-9三甲基氰硅烷

59146-67-76-氰基-2,3-二甲基吡啶

参考文献

Tachdjian, Catherine; Patron, Andrew P.; Adamski-Werner, Sara L.; Bakir, Farid; Chen, Qing; Darmohusodo, Vincent; Hobson, Stephen Terrence; Li, Xiaodong; Qi, Ming; Rogers, Daniel Harry; Rinnova, Marketa; Servant, Guy; Tang, Xiao-Qing; Zoller, Mark; Wallace, David; Xing, Amy; Gubernator, Klaus
Patent: US2005/84506 A1, 2005 ;
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59146-67-76-氰基-2,3-二甲基吡啶

参考文献

Merck Frosst Canada, Inc.
Patent: US5506227 A1, 1996 ;
US 5506227 A

参考文献

Kant, Joydeep; Popp, Frank D.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 425 - 427

7677-24-9三甲基氰硅烷+

1711-06-4间甲基苯甲酰氯

5955-74-83-甲基苯甲酰基丁酯

参考文献

Olah, George A.; Arvanaghi, Massoud; Prakash, G. K. Surya
Synthesis, 1983 , # 8 p. 636 - 637

7677-24-9三甲基氰硅烷

60011-55-45-甲氧基-2-甲基-1-(苯基甲基)-1H-吲哚-3-乙腈

参考文献

Maguire, Anita R.; Plunkett, Stephen J.; Papot, Sebastien; Clynes, Martin; O'Connor, Robert; Touhey, Samantha
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 3 p. 745 - 762

67-56-1甲醇+

3612-20-2N-苄基哌啶酮+

7677-24-9三甲基氰硅烷

60437-30-11-苄基-4-羟基哌啶-4-羧酸甲酯

参考文献

G.D. SEARLE and CO.
Patent: EP1221441 A2, 2002 ;
Location in patent: Page 201-202 ;

2579-22-8苯丙炔醛+

7677-24-9三甲基氰硅烷

6047-90-1

参考文献

Choi, Hyung Ho; Son, Young Hoon; Jung, Min Seok; Kang, Eun Joo
Tetrahedron Letters, 2011 , vol. 52, # 18 p. 2312 - 2315