5-羟基-2-[[4-羟基-3-(三氟甲基)苯基]氨基]苯甲酸合成路线 （共 8 条）
反应条件
hydrogen; palladium on activated charcoal in methanol
参考文献
Boltze; Backer; Kreisfeld
Arzneimittel-Forschung/Drug Research, 1982 , vol. 32, # 3 p. 183 - 186
反应条件
1: 97 percent / H2 / Pt
2: 1) NaNO2
3: 87 percent / NaOH
4: 73.4 percent / K2CO3 / Cu powder / 2 h / 160 °C
5: 93.6 percent / H2 / 10percent Pd/C / methanol
View Scheme
参考文献
Boltze; Backer; Kreisfeld
Arzneimittel-Forschung/Drug Research, 1982 , vol. 32, # 3 p. 183 - 186
反应条件
1: 98.8 percent / H2 / Pt
2: 73.4 percent / K2CO3 / Cu powder / 2 h / 160 °C
3: 93.6 percent / H2 / 10percent Pd/C / methanol
View Scheme
参考文献
Boltze; Backer; Kreisfeld
Arzneimittel-Forschung/Drug Research, 1982 , vol. 32, # 3 p. 183 - 186
反应条件
1: 1) NaNO2
2: 87 percent / NaOH
3: 73.4 percent / K2CO3 / Cu powder / 2 h / 160 °C
4: 93.6 percent / H2 / 10percent Pd/C / methanol
View Scheme
参考文献
Boltze; Backer; Kreisfeld
Arzneimittel-Forschung/Drug Research, 1982 , vol. 32, # 3 p. 183 - 186
反应条件
1: 92 percent / benzyltributylammonium bromide, NaOH / 24 h / 55 °C
2: 98.8 percent / H2 / Pt
3: 73.4 percent / K2CO3 / Cu powder / 2 h / 160 °C
4: 93.6 percent / H2 / 10percent Pd/C / methanol
View Scheme
参考文献
Boltze; Backer; Kreisfeld
Arzneimittel-Forschung/Drug Research, 1982 , vol. 32, # 3 p. 183 - 186
反应条件
1: 73.4 percent / K2CO3 / Cu powder / 2 h / 160 °C
2: 93.6 percent / H2 / 10percent Pd/C / methanol
View Scheme
参考文献
Boltze; Backer; Kreisfeld
Arzneimittel-Forschung/Drug Research, 1982 , vol. 32, # 3 p. 183 - 186
反应条件
1: 73.4 percent / K2CO3 / Cu powder / 2 h / 160 °C
2: 93.6 percent / H2 / 10percent Pd/C / methanol
View Scheme
参考文献
Boltze; Backer; Kreisfeld
Arzneimittel-Forschung/Drug Research, 1982 , vol. 32, # 3 p. 183 - 186
反应条件
1: 87 percent / NaOH
2: 73.4 percent / K2CO3 / Cu powder / 2 h / 160 °C
3: 93.6 percent / H2 / 10percent Pd/C / methanol
View Scheme
参考文献
Boltze; Backer; Kreisfeld
Arzneimittel-Forschung/Drug Research, 1982 , vol. 32, # 3 p. 183 - 186
