1: 78 percent / N-bromosuccinimide; water / tetrahydrofuran / 24 h / 20 °C 2: 40 percent 3: 81 percent / t-BuOK / tetrahydrofuran / 24 h / 20 °C 4: 78 percent / 10percent Pd/C / methanol / 20 °C 5: 97 percent / 15 h / Heating View Scheme

1: 78 percent / 10percent Pd/C / methanol / 20 °C 2: 97 percent / 15 h / Heating View Scheme

1: 81 percent / t-BuOK / tetrahydrofuran / 24 h / 20 °C 2: 78 percent / 10percent Pd/C / methanol / 20 °C 3: 97 percent / 15 h / Heating View Scheme

1: NBS / diethyl ether 2: NaOMe / methanol 3: 78 percent / N-bromosuccinimide; water / tetrahydrofuran / 24 h / 20 °C 4: 40 percent 5: 81 percent / t-BuOK / tetrahydrofuran / 24 h / 20 °C 6: 78 percent / 10percent Pd/C / methanol / 20 °C 7: 97 percent / 15 h / Heating View Scheme

1: NaOMe / methanol 2: 78 percent / N-bromosuccinimide; water / tetrahydrofuran / 24 h / 20 °C 3: 40 percent 4: 81 percent / t-BuOK / tetrahydrofuran / 24 h / 20 °C 5: 78 percent / 10percent Pd/C / methanol / 20 °C 6: 97 percent / 15 h / Heating View Scheme

Heating;