反应条件
1: 56.4 percent / 1) sodium hydride / 1) DMF, room temperature, 1 h, 2) room temperature, 3 h 2: 99.8 percent / H2 / Raney Ni / acetic acid / 3 h 3: NaNO2, HOAc / acetic anhydride / 4 h / 0 °C 4: CCl4 / 5 h / Heating 5: 1) LiOH*H2O, 2) aqueous HOAc / 1) EtOH, water, room temperature, 1 h, 2) CH2Cl2, room temperature, 24 h 6: 79 percent / 80percent aqueous trifluoroacetic acid / 3 h / Ambient temperature 7: 84.4 percent / 2) p-TsOH / toluene / Heating; 1) 30 min, 2) 3 h View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 1 p. 27 - 31
