2-氧代-4,6-二甲基-1,2-二氢吡啶-3-甲腈合成路线 （共 62 条）
参考文献
Journal of Heterocyclic Chemistry, , vol. 24, p. 709 - 713
反应条件
1: ethanol / -20 °C 2: tetrahydrofuran / -10 - 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 64, # 26 p. 9493 - 9498
参考文献
Tetrahedron Letters, , vol. 42, # 51 p. 8981 - 8984
反应条件
sulfuric acid 5 h; Heating;
参考文献
Chemische Berichte, , vol. 122, p. 669 - 676
反应条件
1: PCl5; POCl3 2: concentrated aqueous NH3 / 160 °C View Scheme
参考文献
Vanderhorst; Hamilton
Journal of the American Chemical Society, 1953 , vol. 75, p. 656
Full Text View citing articles Show Details
Dornow; Neuse
Archiv der Pharmazie (Weinheim, Germany), 1955 , vol. 288, p. 174,182
反应条件
1: 95 percent / Bromine / acetic acid / 0.5 h 2: 86 percent / POCl3/PCl5 / 8 h / Heating View Scheme
参考文献
Thompson, Wayne J.; Gaudino, John
Journal of Organic Chemistry, 1984 , vol. 49, # 26 p. 5237 - 5243
反应条件
1: trichlorophosphate; triethylamine / acetonitrile / 3 h / |Reflux 2: hydrazine hydrate / ethanol / 5 h / 20 °C 3: hydrazine hydrate / N,N-dimethyl-formamide / 3 h / |Reflux View Scheme
参考文献
Waly, Mohamed A.; El-Hawary, Ibrahim I.; Hamama, Wafaa S.; Zoorob, Hanafi H.
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # SUPPL.1 p. E12-E17
反应条件
1: 94 percent / sulfuryl chloride / CCl4 / 6 h / Heating 2: 76 percent / POCl3 / Heating View Scheme
参考文献
BIAL - PORTELA and Cª., S.A.; RUSSO, Domenico; KISS, Laszlo Erno; WAHNON, Jorge Bruno Reis; LEARMONTH, David Alexander; ESZENYI, Tibor; ZIMMERMANN, Axel; SCHLUMMER, Bjoern; KREIS, Michael; REITER, Klaus
Patent: WO2013/89573 A1, 2013 ;
反应条件
sulfuryl dichloride in tetrachloromethane 6 h; Heating;
参考文献
Dyadyuchenko; Strelkov; Mikhailichenko; Zaplishny
Chemistry of Heterocyclic Compounds, 2004 , vol. 40, # 3 p. 308 - 314
反应条件
silver carbonate in benzene 48 h;
参考文献
Journal of Organic Chemistry, , vol. 68, # 9 p. 3446 - 3453
