1: n-BuLi / tetrahydrofuran; hexane / 0.33 h / 0 - 5 °C
2: tetrahydrofuran / 4 h / Ambient temperature; var. alkyl halides, C-1/C-3 ratio of alkylated products
View Scheme
参考文献
Trimitsis, G. B.; Hinkley, J. M.; TenBrink, R.; Faburada, A. L.; Anderson, R.; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 18 p. 2957 - 2962
sodium hydride in N,N,N',N',N'',N''-hexamethylphosphoric triamide
T=20°C; Yield given. Yields of byproduct given. Title compound not separated from byproducts;