2-[(二甲基氨基)甲基]环己酮合成路线 （共 38 条）
反应条件
1: 76 percent / sodium hydride / 1,2-dimethoxy-ethane 2: mercuric perchlorate / CHCl3; tetrahydrofuran / Ambient temperature 3: acetic acid / Heating View Scheme
参考文献
Ozaki; Oshio; Ohsuga; Kaburagi; Sung; Kim
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 5 p. 1132 - 1136
反应条件
2: hydroxylamine hydrochloride; ethanol View Scheme
参考文献
Gill et al.
Journal of the American Chemical Society, 1952 , vol. 74, p. 4923,4927
反应条件
sodium hydroxide in water T=96 - 98°C; 5 h; Yield given;
参考文献
Akimova, T. I.; Kosenko, S. V.; Tilichenko, M. N.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 12 p. 2271 - 2277
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 12 p. 2553 - 2560
反应条件
sodium hydroxide in water T=90 - 100°C; 5 h; Further byproducts given;
参考文献
Akimova, T. I.; Kosenko, S. V.; Tilichenko, M. N.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 12 p. 2271 - 2277
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 12 p. 2553 - 2560
反应条件
T=110 - 130°C; 3 h; Further byproducts given;
参考文献
Akimova, T. I.; Kosenko, S. V.; Tilichenko, M. N.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 12 p. 2271 - 2277
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 12 p. 2553 - 2560
参考文献
Chemische Berichte, , vol. 53, p. 1876
参考文献
Chemische Berichte, , vol. 53, p. 1876
反应条件
1: ethanol
2: sulfur
3: sulfur
View Scheme
参考文献
Grandberg et al.
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 2537,2540; engl. Ausg. S. 2499, 2502
反应条件
1: 1.) potassium tert-butoxide, 2.) 18-crown-6 ether / 1.) THF, 2.) 8-10 h
2: diethyl ether
3: 1.) Ag2O / 1.) H2O, 6 h, 2.) 60-90 deg C, 1E-3 mmHg, 30 min; to 120 deg C
View Scheme
参考文献
van Straten,J.W. et al.
Recueil des Travaux Chimiques des Pays-Bas, 1978 , vol. 97, p. 105 - 106
反应条件
1: ethanolic sodium ethylate
2: ethanolic KOH-solution / Erhitzen des Reaktionsprodukts
View Scheme
参考文献
Mannich; Koch
Chemische Berichte, 1942 , vol. 75, p. 803
