1: (3R,6S)-3-amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one; chloroformic acid 4-nitrophenyl ester With triethylamine in tetrahydrofuran T=0°C; 2: 2-oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine dihydrochloride With triethylamine in tetrahydrofuran; chloroform T=25°C;
参考文献
Burgey, Christopher S.; Paone, Daniel V.; Shaw, Anthony W.; Deng, James Z.; Nguyen, Diem N.; Potteiger, Craig M.; Graham, Samuel L.; Vacca, Joseph P.; Williams, Theresa M.
Organic Letters, 2008 , vol. 10, # 15 p. 3235 - 3238
