hydrogenchloride in diethyl ether T=0°C;

1: 78 percent / SOCl2 2: Et3N / 6 h / 0 °C 3: 76.3 percent / LiOH*H2O, H2O / tetrahydrofuran; methanol / 5 h / 60 °C / various bases, other time and temperature 4: 71 percent / HCl(g) / diethyl ether / 0 °C View Scheme

1: Et3N, CCl4 / CH2Cl2 / 10 h / 0 °C 2: Et3N / 6 h / 0 °C 3: 76.3 percent / LiOH*H2O, H2O / tetrahydrofuran; methanol / 5 h / 60 °C / various bases, other time and temperature 4: 71 percent / HCl(g) / diethyl ether / 0 °C View Scheme

1: 76.3 percent / LiOH*H2O, H2O / tetrahydrofuran; methanol / 5 h / 60 °C / various bases, other time and temperature 2: 71 percent / HCl(g) / diethyl ether / 0 °C View Scheme