吡唑并[1,5-a]吡啶-2-甲醇合成路线 (共 2 条)
反应条件
1: With dimethylsulfide borane complex in tetrahydrofuran; toluene T=0 - 65°C; 5.5 h; Inert atmosphere; 2: With hydrogenchloride in tetrahydrofuran; water; toluene 2 h; Reflux; 3: With sodium hydroxide in tetrahydrofuran; water; toluene
参考文献
LABORATORIOS DEL DR. ESTEVE S.A.; DIAZ FERNANDEZ, José Luis; CUBERES ALTISENT, Mª Rosa
Patent: WO2013/124341 A1, 2013 ;
Location in patent: Page/Page column 35-36 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide 6 h; Ambient temperature;
参考文献
Tsuchiya, Takashi; Sashida, Haruki
Journal of the Chemical Society, Chemical Communications, 1980 , # 23 p. 1109 - 1110