3,4-二氢-8-羟基-1(2H)-萘酮合成路线 （共 8 条）
反应条件
1: 82 percent / K3PO4 / dimethylsulfoxide / 0.33 h / 60 °C 2: 2.) 0.4M aq. H2SO4 / 1.) CH3CN, irrad., 60 min, 2.) EtOH, RT, 30 min View Scheme
参考文献
Sharshira, Essam Mohamed; Iwanami, Haruki; Okamura, Mutsuo; Hasegawa, Eietsu; Horaguchi, Takaaki
Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 1 p. 17 - 25
反应条件
potassium carbonate in acetone 30 h; Heating;
参考文献
Bilger, Christine; Demerseman, Pierre; Royer, Rene
European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 363 - 365
反应条件
potassium phosphate in dimethyl sulfoxide T=60°C; 0.333333 h;
参考文献
Sharshira, Essam Mohamed; Iwanami, Haruki; Okamura, Mutsuo; Hasegawa, Eietsu; Horaguchi, Takaaki
Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 1 p. 17 - 25
反应条件
1: 92 percent / K2CO3 / acetone / 30 h / Heating 2: 93 percent / NaOMe / benzene 3: 75 percent / dichlorodicyanobenzoquinone / dioxane / 20 °C 4: K2CO3 / acetone / 24 h / 20 °C 5: Ac2O / 1 h / Heating View Scheme
参考文献
Bilger, Christine; Demerseman, Pierre; Royer, Rene
European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 363 - 365
反应条件
boron trichloride in hexane; dichloromethane
T=-78°C; 0.5 h;
参考文献
Miyashita, Kazuyuki; Sakai, Takayuki; Imanishi, Takeshi
Organic letters, 2003 , vol. 5, # 15 p. 2683 - 2686
反应条件
ethanol; nickel
Hydrogenation;
参考文献
Hochstein et al.
Journal of the American Chemical Society, 1953 , vol. 75, p. 5455,5474
反应条件
trifluorormethanesulfonic acid
48 h; Heating;
参考文献
Kozelj, Matjaz; Petric, Andrej
Synlett, 2007 , # 11 p. 1699 - 1702
反应条件
potassium phosphate in dimethyl sulfoxide
T=60°C; 0.333333 h;
参考文献
Sharshira, Essam Mohamed; Iwanami, Haruki; Okamura, Mutsuo; Hasegawa, Eietsu; Horaguchi, Takaaki
Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 1 p. 17 - 25
