in HNO3 (white fumming)

sodium hydroxide; 1,3,5-trishydroxybenzene; copper(II) sulfate

1: thionyl chloride / N,N-dimethyl-formamide / toluene / 3 h / 50 °C 2: ammonia / toluene; water 3: phosphorous pentoxide / chloroform / 12 h / Reflux View Scheme

1: With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.5 h; 2: With iodine in tetrahydrofuran T=-78 - 20°C; 3 h;

2: CuCN; pyridine 3: aqueous H2SO4 View Scheme

sulfuric acid 18 h; Heating / reflux;

sulfuric acid in methanol; ethyl acetate

in methanol; diethyl ether; toluene 2 h; Inert atmosphereSchlenk technique;

暂无反应条件数据

1.1: lithium hydroxide hydrate; tris-(dibenzylideneacetone)dipalladium(0) / water; 1-methyl-pyrrolidin-2-one / 24 h / 65 °C / |Inert atmosphere; |Schlenk technique 2.1: palladium diacetate; N-acetyl-glycine; potassium acetate; [bis(acetoxy)iodo]benzene / tert-butyl alcohol / 12 h / 80 °C / |Sealed tube 3.1: sodium methylate / tetrahydrofuran / 1 h / 35 °C / |Cooling with ice 3.2: 45 °C 3.3: 6 h / 55 °C 4.1: palladium diacetate; N-acetyl-glycine; potassium acetate; [bis(acetoxy)iodo]benzene / tert-butyl alcohol / 12 h / 100 °C / |Sealed tube View Scheme