6-氨基-4-(4-氯-苯基)-3-甲基-1-苯基-1,4-二氢-吡喃o[2,3-c]吡唑-5-甲腈合成路线 (共 8 条)
反应条件
N-benzyl-N,N,N-triethylammonium chloride in water
T=90°C; 6 h;
参考文献
Shi, Daqing; Mou, Jie; Zhuang, Qiya; Niu, Lihui; Wu, Nan; Wang, Xiangshan
Synthetic Communications, 2004 , vol. 34, # 24 p. 4557 - 4563
反应条件
magnesium oxide in acetonitrile
Michael addition; 0.333333 h; Reflux;
参考文献
Sheibani, Hassan; Babaie, Maryam
Synthetic Communications, 2010 , vol. 40, # 2 p. 257 - 265
反应条件
L-proline
T=50°C; Ionic liquid;
参考文献
Khurana, Jitender M.; Nand, Bhaskara; Kumar, Sanjay
Synthetic Communications, 2011 , vol. 41, # 3 p. 405 - 410
反应条件
magnesium oxide in acetonitrile
Michael addition; 0.0833333 h; Reflux;
参考文献
Sheibani, Hassan; Babaie, Maryam
Synthetic Communications, 2010 , vol. 40, # 2 p. 257 - 265
反应条件
triethylamine in benzene
2 h;
参考文献
Tacconi, G.; Gatti, G.; Desimoni G.; Messori, V.
Journal fuer Praktische Chemie (Leipzig), 1980 , vol. 322, # 5 p. 831 - 834
反应条件
morpholine in methanol
Yield given;
参考文献
Sharanina, L. G.; Promonenkov, V. K.; Marshtupa, V. P.; Pashchenko, A. V.; Puzanova, V. V.; et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982 , vol. 18, # 6 p. 607 - 611
Khimiya Geterotsiklicheskikh Soedinenii, 1982 , vol. 18, # 6 p. 801 - 806
反应条件
1: 90 percent / methanol
2: Morpholine / methanol
View Scheme
参考文献
Sharanina, L. G.; Promonenkov, V. K.; Marshtupa, V. P.; Pashchenko, A. V.; Puzanova, V. V.; et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982 , vol. 18, # 6 p. 607 - 611
Khimiya Geterotsiklicheskikh Soedinenii, 1982 , vol. 18, # 6 p. 801 - 806
反应条件
1: 90 percent / methanol
2: Morpholine / methanol
View Scheme
参考文献
Sharanina, L. G.; Promonenkov, V. K.; Marshtupa, V. P.; Pashchenko, A. V.; Puzanova, V. V.; et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982 , vol. 18, # 6 p. 607 - 611
Khimiya Geterotsiklicheskikh Soedinenii, 1982 , vol. 18, # 6 p. 801 - 806