2-(氨基甲基)-3,5-二甲基苯酚合成路线 （共 4 条）
反应条件
sodium hydroxide; hydrogen; palladium on activated charcoal in water
P=1551.4 Torr;
参考文献
Stokker; Deana; deSolms; Schultz; Smith; Cragoe Jr.; Baer; Ludden; Russo; Scriabine; Sweet; Watson
Journal of Medicinal Chemistry, 1980 , vol. 23, # 12 p. 1414 - 1427
反应条件
1: conc. H2SO4, HOAc / 16 h / 22 °C
2: conc. HCl / ethanol / 1.5 h / Heating
3: NaOH, H2 / 5percent Pd/C / H2O / 1551.4 Torr
View Scheme
参考文献
Stokker; Deana; deSolms; Schultz; Smith; Cragoe Jr.; Baer; Ludden; Russo; Scriabine; Sweet; Watson
Journal of Medicinal Chemistry, 1980 , vol. 23, # 12 p. 1414 - 1427
参考文献
Zigeuner; Jellinek
Monatshefte fuer Chemie, 1959 , vol. 90, p. 297,301
反应条件
1: Raney nickel; ethanol / Hydrogenation
2: aq.-ethanolic HCl
View Scheme
参考文献
Zigeuner; Jellinek
Monatshefte fuer Chemie, 1959 , vol. 90, p. 297,301
