in formamide T=100°C; 16 h;

ammonium hydroxide in methanol; ethyl acetate 16 h; Ambient temperature;

1: 94 percent Turnov. / N-bromosuccinimide, benzoyl peroxide / chlorobenzene / 24 h / Heating 2: 64.8 percent / conc. aq. NH3 / methanol; ethyl acetate / 16 h / Ambient temperature View Scheme

1: 71 percent / dimethylformamide / 2 h / 80 - 85 °C 2: 90 percent / formamide / 16 h / 100 °C View Scheme