1,3-二溴-5,5-二甲基海因合成路线 （共 64 条）
反应条件
1: in ethyl acetate 2.5 h; Refluxing; 2: in tetrahydrofuran
参考文献
Eastman Kodak Company
Patent: US2005/245752 A1, 2005 ;
Location in patent: Page/Page column 8 ;
反应条件
trifluorormethanesulfonic acid in dichloromethane; ethyl acetate
参考文献
US2002/55631 A1, ;
US 20020055631 A1
参考文献
Salvi
Rev. Fac. Cienc. quim. Univ. La Plata, 1950 , vol. 25, p. 49,52
参考文献
Orazi; Meseri
Anales de la Asociacion Quimica Argentina (1921-2001), 1949 , vol. 37, p. 263,266
Anales de la Asociacion Quimica Argentina (1921-2001), 1950 , vol. 38, p. 5,10
反应条件
sulfuric acid in water T=0°C; 0.0833333 h;
参考文献
Advanced Synthesis and Catalysis, , vol. 355, # 2-3 p. 499 - 507
参考文献
Salvi
Rev. Fac. Cienc. quim. Univ. La Plata, 1950 , vol. 25, p. 49,52
参考文献
Orazi et al.
Anales de la Asociacion Quimica Argentina (1921-2001), 1952 , vol. 40, p. 61,71
反应条件
sodium hydroxide in water
参考文献
Radhakrishnan, K.; Indrasenan, P.
Journal of the Indian Chemical Society, 1985 , vol. 62, p. 84 - 86
参考文献
Orazi; Salellas
Anales de la Asociacion Quimica Argentina (1921-2001), 1950 , vol. 38, p. 188,191
反应条件
1: pyrene; 1,3-dibromo-5,5-dimethyl-hydantoin in dichloromethane
T=20°C; 1 h;
2: diphenylamine With tri-tert-butyl phosphine; palladium diacetate; caesium carbonate in o-xylene
T=120°C; Buchwald-Hartwig Coupling; 48 h; Overall yield = 68 percent; Overall yield = 205 mg;
参考文献
Hu, Jian-Yong; Feng, Xing; Seto, Nobuyuki; Do, Jung-Hee; Zeng, Xi; Tao, Zhu; Yamato, Takehiko
Journal of Molecular Structure, 2013 , vol. 1035, p. 19 - 26
