熊果酸合成路线 - 魔法化学

参考文献

Siewert, Bianka; Pianowski, Elke; Obernauer, Anja; Csuk, Rene
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 594 - 615

77-52-1熊果酸

508-02-1齐墩果酸+

915-32-23-羟基-(3alpha)-乌苏-12-烯-28-酸甲酯+

1724-17-0齐墩果酸甲酯

参考文献

Tetrahedron Letters, , vol. 46, # 13 p. 2337 - 2340

77-52-1熊果酸+

74-88-4甲基碘

915-32-23-羟基-(3alpha)-乌苏-12-烯-28-酸甲酯

参考文献

Leal, Ana S.; Salvador, Jorge A. R.; Wang, Rui; Jing, Yongkui
ChemMedChem, 2012 , vol. 7, # 9 p. 1635 - 1646,12

186581-53-3重氮甲烷+

77-52-1熊果酸

915-32-23-羟基-(3alpha)-乌苏-12-烯-28-酸甲酯

参考文献

Mallavadhani, Uppuluri V.; Mahapatra, Anita; Pattnaik, Banita; Vanga, Nagireddy; Suri, Nitasha; Saxena, Ajit K.
Medicinal Chemistry Research, 2013 , vol. 22, # 3 p. 1263 - 1269

74-83-9溴甲烷+

77-52-1熊果酸

915-32-23-羟基-(3alpha)-乌苏-12-烯-28-酸甲酯

参考文献

Siewert, Bianka; Wiemann, Jana; Koewitsch, Alexander; Csuk, Rene
European Journal of Medicinal Chemistry, 2014 , vol. 72, p. 84 - 101

77-52-1熊果酸+

18107-18-1三甲基硅烷化重氮甲烷

915-32-23-羟基-(3alpha)-乌苏-12-烯-28-酸甲酯

参考文献

Ma, Chaomei; Nakamura, Norio; Miyashiro, Hirotsugu; Hattori, Masao; Shimotohno, Kunitada
Chemical and Pharmaceutical Bulletin, 1999 , vol. 47, # 2 p. 141 - 145

77-52-1熊果酸

915-32-23-羟基-(3alpha)-乌苏-12-烯-28-酸甲酯

参考文献

WELLINGTON LABORATORIES INC.
Patent: WO2008/68 A1, 2008 ;
Location in patent: Page/Page column 12-13 ;

77-52-1熊果酸+

77-78-1硫酸二甲酯

915-32-23-羟基-(3alpha)-乌苏-12-烯-28-酸甲酯

参考文献

Orr et al.
Journal of the American Pharmaceutical Association (1912-1977), 1945 , vol. 34, p. 39,40
Full Text Show Details
Ishidate; Tamura; Okada
Yakugaku Zasshi, 1947 , vol. 67, p. 206
Chem.Abstr., 1951 , p. 9069

77-52-1熊果酸

508-02-1齐墩果酸+

915-32-23-羟基-(3alpha)-乌苏-12-烯-28-酸甲酯+

1724-17-0齐墩果酸甲酯

参考文献

Tetrahedron Letters, , vol. 46, # 13 p. 2337 - 2340

77-52-1熊果酸

545-48-2高根二醇

参考文献

Kazakova; Giniyatullina; Tolstikov; Baikova; Zaprutko; Apryshko
Russian Journal of Bioorganic Chemistry, 2011 , vol. 37, # 3 p. 369 - 379