1,1,1-三(羟甲基)乙烷合成路线 （共 76 条）
反应条件
1: 20percent KOH in ethanol / various solvent(s) / 0.25 h / Heating
2: 75 percent / pyridine / CH2Cl2 / 0 °C
View Scheme
参考文献
Corey, E. J.; Raju, Natarajan
Tetrahedron Letters, 1983 , vol. 24, # 50 p. 5571 - 5574
反应条件
1: 20percent KOH in ethanol / various solvent(s) / 0.25 h / Heating
2: 84 percent / pyridine / CH2Cl2 / 0 °C
View Scheme
参考文献
Corey, E. J.; Raju, Natarajan
Tetrahedron Letters, 1983 , vol. 24, # 50 p. 5571 - 5574
反应条件
1: 20percent KOH in ethanol / various solvent(s) / 0.25 h / Heating
2: pyridine / CH2Cl2 / 0 °C
View Scheme
参考文献
Corey, E. J.; Raju, Natarajan
Tetrahedron Letters, 1983 , vol. 24, # 50 p. 5571 - 5574
反应条件
1: 20percent KOH in ethanol / various solvent(s) / 0.25 h / Heating
2: pyridine / CH2Cl2 / 0 °C
View Scheme
参考文献
Corey, E. J.; Raju, Natarajan
Tetrahedron Letters, 1983 , vol. 24, # 50 p. 5571 - 5574
反应条件
1: 20percent KOH in ethanol / various solvent(s) / 0.25 h / Heating
2: pyridine / CH2Cl2 / 0 °C
3: 91 percent / BF3*Et2O / CH2Cl2 / 4 h / -15 °C
View Scheme
参考文献
Corey, E. J.; Raju, Natarajan
Tetrahedron Letters, 1983 , vol. 24, # 50 p. 5571 - 5574
反应条件
1: 20percent KOH in ethanol / various solvent(s) / 0.25 h / Heating
2: pyridine / CH2Cl2 / 0 °C
3: 90 percent / BF3*Et2O / CH2Cl2 / 10 h / -15 °C
View Scheme
参考文献
Corey, E. J.; Raju, Natarajan
Tetrahedron Letters, 1983 , vol. 24, # 50 p. 5571 - 5574
反应条件
1: 20percent KOH in ethanol / various solvent(s) / 0.25 h / Heating
2: pyridine / CH2Cl2 / 0 °C
3: 90 percent / BF3*Et2O / CH2Cl2 / 10 h / -15 °C
4: 95 percent / iodine-silver trifluoroacetate
View Scheme
参考文献
Corey, E. J.; Raju, Natarajan
Tetrahedron Letters, 1983 , vol. 24, # 50 p. 5571 - 5574
反应条件
toluene-4-sulfonic acid in toluene
2 h; Dean-StarkReflux;
参考文献
Tsotsalas, Manuel; Liu, Jinxuan; Tettmann, Beatrix; Grosjean, Sylvain; Shahnas, Artak; Wang, Zhengbang; Azucena, Carlos; Addicoat, Matthew; Heine, Thomas; Lahann, Joerg; Overhage, Joerg; Braese, Stefan; Gliemann, Hartmut; Woell, Christof
Journal of the American Chemical Society, 2014 , vol. 136, # 1 p. 8 - 11
反应条件
tributyl-amine in diethylene glycol dimethyl ether
T=150°C; 12 h; Inert atmosphere;
参考文献
Ren, Wei; Emi; Yamane, Motoki
Synthesis, 2011 , # 14 art. no. F31611SS, p. 2303 - 2309
参考文献
Doering; Levy
Journal of the American Chemical Society, 1955 , vol. 77, p. 509,512
