3-(2-溴乙基)-1H-喹唑啉-2,4-二酮合成路线 （共 10 条）
反应条件
hydrogen bromide
0.0333333 h; steam bath;
参考文献
Papadopoulos, Eleftherios Paul
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 6 p. 1553 - 1558
反应条件
1: 5.1 g / conc. aq. HCl / 0.05 h / steam bath
2: 10percent aq. KHCO3 / 0.5 h / Ambient temperature
3: 0.45 percent / H2O / acetone / 0.5 h / Heating
4: 90 percent / 10percent aq. KHCO3 / 0.5 h / steam bath
5: 90 percent / aq. HBr / 0.03 h / steam bath
View Scheme
参考文献
Papadopoulos, Eleftherios Paul
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 6 p. 1553 - 1558
反应条件
1: 10percent aq. KHCO3 / 0.5 h / Ambient temperature
2: 0.45 percent / H2O / acetone / 0.5 h / Heating
3: 90 percent / 10percent aq. KHCO3 / 0.5 h / steam bath
4: 90 percent / aq. HBr / 0.03 h / steam bath
View Scheme
参考文献
Papadopoulos, Eleftherios Paul
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 6 p. 1553 - 1558
反应条件
1: 0.45 percent / H2O / acetone / 0.5 h / Heating
2: 90 percent / 10percent aq. KHCO3 / 0.5 h / steam bath
3: 90 percent / aq. HBr / 0.03 h / steam bath
View Scheme
参考文献
Papadopoulos, Eleftherios Paul
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 6 p. 1553 - 1558
反应条件
1: 48 h / Ambient temperature
2: 5.1 g / conc. aq. HCl / 0.05 h / steam bath
3: 10percent aq. KHCO3 / 0.5 h / Ambient temperature
4: 0.45 percent / H2O / acetone / 0.5 h / Heating
5: 90 percent / 10percent aq. KHCO3 / 0.5 h / steam bath
6: 90 percent / aq. HBr / 0.03 h / steam bath
View Scheme
参考文献
Papadopoulos, Eleftherios Paul
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 6 p. 1553 - 1558
反应条件
1: 95 percent / conc. aq. ammonia / ethanol / 0.25 h / steam bath
2: 90 percent / aq. HBr / 0.03 h / steam bath
View Scheme
参考文献
Papadopoulos, Eleftherios Paul
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 6 p. 1553 - 1558
反应条件
1: 100 percent / 16 h / Ambient temperature
2: 95 percent / conc. aq. ammonia / ethanol / 0.25 h / steam bath
3: 90 percent / aq. HBr / 0.03 h / steam bath
View Scheme
参考文献
Papadopoulos, Eleftherios Paul
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 6 p. 1553 - 1558
反应条件
1: 90 percent / 10percent aq. KHCO3 / 0.5 h / steam bath
2: 90 percent / aq. HBr / 0.03 h / steam bath
View Scheme
参考文献
Papadopoulos, Eleftherios Paul
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 6 p. 1553 - 1558
反应条件
1: 10percent aq. KHCO3 / 0.07 h
2: 90 percent / 10percent aq. KHCO3 / 0.5 h / steam bath
3: 90 percent / aq. HBr / 0.03 h / steam bath
View Scheme
参考文献
Papadopoulos, Eleftherios Paul
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 6 p. 1553 - 1558
反应条件
1: 83 percent / 10percent aq. NaOH / 0.5 h
2: 90 percent / aq. HBr / 0.03 h / steam bath
View Scheme
参考文献
Papadopoulos, Eleftherios Paul
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 6 p. 1553 - 1558
