1-羟基-2-氧代-1,2,3,4-四氢喹啉合成路线 （共 15 条）
反应条件
1: 1) NaNO2, hydrobromic acid, 2) CuBr / 1) acetone-water, below 8 deg C
2: 38 percent / conc. HCl, H2 / 5percent Pt/C sulfided / methanol; H2O / 2699.3 Torr / 1-2 h
View Scheme
参考文献
McCord; DuBose; Shafer; Davis
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 3 p. 643 - 646
反应条件
1: palladium diacetate; triphenylphosphine; triethylamine
2: hydrogen; Wilkinson's catalyst / tetrahydrofuran; tert-butyl alcohol / 48 h / 1551.49 Torr
3: Ru(bpy)3Cl2*6H2O; 2,6-dimethyl-3,5-diacetyl-1,4-dihydropyridine; acetic acid / N,N-dimethyl-formamide / 16 h / |Irradiation
View Scheme
参考文献
Cismesia, Megan A.; Ischay, Michael A.; Yoon, Tehshik P.
Synthesis (Germany), 2013 , vol. 45, # 19 art. no. 3889, p. 2699 - 2705
反应条件
2,6-dimethyl-3,5-diacetyl-1,4-dihydropyridine; Ru(bpy)3Cl2*6H2O; acetic acid in N,N-dimethyl-formamide
16 h; Irradiation; Reagent/catalyst; chemoselective reaction;
参考文献
Cismesia, Megan A.; Ischay, Michael A.; Yoon, Tehshik P.
Synthesis (Germany), 2013 , vol. 45, # 19 art. no. 3889, p. 2699 - 2705
反应条件
dihydrogen peroxide; copper(II) oxide in methanol
24 h; Ambient temperatureother catalysts, other solvents, other times investigated; Product distributionMechanism;
参考文献
Murahashi, Shun-Ichi; Oda, Tetsuya; Sugahara, Toshiaki; Masui, Yoshiyuki
Journal of Organic Chemistry, 1990 , vol. 55, # 6 p. 1744 - 1749
反应条件
in acetic acid
0.5 h; Heating;
参考文献
Hashimoto; Ishizaki; Shudo; Okamoto
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 11 p. 3891 - 3896
