4-羟基-2H-1,4-苯并噁嗪-3(4h)-酮合成路线 （共 21 条）
反应条件
palladium diacetate; triethylammonium formate; triphenylphosphine in ethanol; water
0.166667 h; Heating;
参考文献
Kikugawa, Yasuo; Shimada, Masahiro; Matsumoto, Kazuhiro
Heterocycles, 1994 , vol. 37, # 1 p. 293 - 302
反应条件
1: 82 percent / 0.5 h / Heating
2: 88 percent / aq. NH4Cl, Zn / ethanol / 2 h / 30 - 40 °C
View Scheme
参考文献
Sicker; Pratorius; Mann; Meyer
Synthesis, 1989 , # 3 p. 211 - 212
反应条件
(i) KBH4, aq. HCl, Pd-C, H2O, (Me)2CHCH2Ac, (ii) aq. HCl, (iii) KOAc; Multistep reaction;
参考文献
Johnson; Panetta; Smith
The Journal of organic chemistry, 1966 , vol. 31, # 8 p. 2560 - 2564
反应条件
(electrochemical reduction);
参考文献
Tallec,A. et al.
Comptes Rendus des Seances de l'Academie des Sciences, Serie C: Sciences Chimiques, 1971 , vol. 273, p. 1378 - 1381
反应条件
1: LDA / toluene; hexane / 3 h / -70 °C
2: MCPBA / CH2Cl2 / 2 h / -5 °C
3: Bu4NF*3H2O / tetrahydrofuran / 2 h / 25 °C
View Scheme
参考文献
Sicker; Pratorius; Mann; Meyer
Synthesis, 1989 , # 3 p. 211 - 212
反应条件
1: 40 percent / 5percent aq. NaCO3 / CH2Cl2 / 0.08 h
2: 8 percent / benzene / 24 h / Heating
3: NaOH / Ambient temperature
View Scheme
参考文献
Hashimoto; Ishizaki; Shudo; Okamoto
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 11 p. 3891 - 3896
反应条件
1: 40 percent / 5percent aq. NaCO3 / CH2Cl2 / 0.08 h
2: 8 percent / benzene / 24 h / Heating
View Scheme
参考文献
Hashimoto; Ishizaki; Shudo; Okamoto
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 11 p. 3891 - 3896
反应条件
1: 40 percent / 5percent aq. NaCO3 / CH2Cl2 / 0.08 h
2: 15 percent / CF3COOH / benzene / 24 h / Ambient temperature
View Scheme
参考文献
Hashimoto; Ishizaki; Shudo; Okamoto
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 11 p. 3891 - 3896
反应条件
1: 40 percent / 5percent aq. NaCO3 / CH2Cl2 / 0.08 h
2: 78 percent / acetic acid / 0.5 h / Heating
View Scheme
参考文献
Coutts,R.T.; Pound,N.J.
Journal of the Chemical Society [Section] C: Organic, 1971 , p. 2696 - 2699
参考文献
Coutts,R.T.; Pound,N.J.
Journal of the Chemical Society [Section] C: Organic, 1971 , p. 2696 - 2699
