2-甲基-4H-1-苯并噻喃-4-酮合成路线 （共 20 条）
反应条件
1: aq. KOH / 0.5 h / 20 °C
2: imidazole / CH2Cl2 / 0 - 20 °C
3: 80 percent / tetrahydrofuran / 16 h / Heating
View Scheme
参考文献
Kumar, Pradeep; Bodas, Mandar S
Tetrahedron, 2001 , vol. 57, # 48 p. 9755 - 9758
反应条件
1.1: NaH / diethyl ether / 0.5 h / 20 °C
1.2: 8.1 g / toluene; diethyl ether / 0.5 h / 20 °C
2.1: 74 percent / 3N HCl / ethanol / 3 h / Heating
3.1: 84 percent / HCl / H2O; ethanol / 3 h / Heating
View Scheme
参考文献
Jung, Jae-Chul; Kim, Ju-Cheun; Park, Oee-Sook
Synthetic Communications, 2000 , vol. 30, # 7 p. 1193 - 1203
反应条件
1: 74 percent / 3N HCl / ethanol / 3 h / Heating
2: 84 percent / HCl / H2O; ethanol / 3 h / Heating
View Scheme
参考文献
Jung, Jae-Chul; Kim, Ju-Cheun; Park, Oee-Sook
Synthetic Communications, 2000 , vol. 30, # 7 p. 1193 - 1203
反应条件
1: 55 percent / LiOH / dimethylformamide / Ambient temperature
2: 81 percent / AlCl3 / benzene / 24 h / 5 - 10 °C
3: 20 percent / sodium / 6 h / Heating
4: 60 percent / ethylenediamine / ethanol / 2 h / Heating
View Scheme
参考文献
Coombes, Richard C.; Fenton, David E.
Phosphorus and Sulfur and the Related Elements, 1982 , vol. 14, p. 139 - 142
反应条件
1: 20 percent / sodium / 6 h / Heating
2: 60 percent / ethylenediamine / ethanol / 2 h / Heating
View Scheme
参考文献
Coombes, Richard C.; Fenton, David E.
Phosphorus and Sulfur and the Related Elements, 1982 , vol. 14, p. 139 - 142
反应条件
1: 81 percent / AlCl3 / benzene / 24 h / 5 - 10 °C
2: 20 percent / sodium / 6 h / Heating
3: 60 percent / ethylenediamine / ethanol / 2 h / Heating
View Scheme
参考文献
Coombes, Richard C.; Fenton, David E.
Phosphorus and Sulfur and the Related Elements, 1982 , vol. 14, p. 139 - 142
反应条件
sodium hydroxide in methanol
参考文献
Nakazumi,H.; Kitao,T.
Bulletin of the Chemical Society of Japan, 1977 , vol. 50, p. 939 - 944
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate
P=1551.4 Torr; 10 h; Ambient temperature;
参考文献
Kumar; Rao; Pandey
Synthetic Communications, 1994 , vol. 24, # 22 p. 3297 - 3306
反应条件
sulfuric acid
T=60°C; 24 h;
参考文献
Nakazumi; Ueyama; Sonoda; Kitao
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 8 p. 2323 - 2324
反应条件
sodium tetrahydroborate; cerium(III) chloride in methanol
5 h; Ambient temperature;
参考文献
Yamaoka, Hiroshi; Hakucho, Tatsushi; Akiba, Kin-ya
Heterocycles, 1981 , vol. 15, # 2 p. 1159 - 1162
