2,3,4,5,6-五氟苯胺合成路线 （共 126 条）
反应条件
sodium hydride in N,N-dimethyl-formamide
T=110 - 120°C; 1 h;
参考文献
Silva, Gloria L.; Ediz, Volkan; Yaron, David; Armitage, Bruce A.
Journal of the American Chemical Society, 2007 , vol. 129, # 17 p. 5710 - 5718
反应条件
in N,N-dimethyl-formamide
2 h; Heating;
参考文献
Zhu, Lei; Zhang, Mingbao
Journal of Organic Chemistry, 2004 , vol. 69, # 21 p. 7371 - 7374
反应条件
CF3SO3H in dichloromethane
参考文献
Abiko, Atsushi; Iwahashi, Hisako
Patent: US2009/176963 A1, 2009 ;
反应条件
in toluene
T=0 - 5°C; 0.5 h;
参考文献
Montazeri, Naser; Pourshamsian, Khalil; Yosefiyan, Soghra; Momeni, Seydeh Samaneh
Journal of Chemical Sciences (Bangalore), 2012 , vol. 124, # 4 p. 883 - 887,5
反应条件
sulfuric acid; sodium nitrite; Na[B(3,5-(CF3)2C6H3)4] in dichloromethane; water
T=0°C;
参考文献
Iwamoto, Hidetoshi; Sonoda, Takaaki; Kobayashi, Hiroshi
Journal of Fluorine Chemistry, 1984 , vol. 24, p. 535 - 537
反应条件
1: 81 percent / nitrosonium tetrafluoroborate / acetonitrile / 1 h / -30 °C
2: 95 percent / acetonitrile / 1 h / -40 °C
View Scheme
参考文献
Kosynkin, Dmitry; Bockman, T. Michael; Kochi, Jay K.
Journal of the Chemical Society. Perkin Transactions 2, 1997 , # 10 p. 2003 - 2012
反应条件
1: |Reflux
2: NiCl2*2phen; zinc / 1-methyl-pyrrolidin-2-one; water / 7 h / 70 °C / |Inert atmosphere
View Scheme
参考文献
Prikhodko; Adonin; Parmon
Russian Chemical Bulletin, 2009 , vol. 58, # 11 p. 2304 - 2310
Izv. Akad. Nauk, Ser. Khim., 2009 , # 11 p. 2234 - 2239,6
反应条件
1: 1,4-dioxane
2: HI
View Scheme
参考文献
Gmelin Handbook: F: PerFHalOrg.7, 1, page 1 - 84
反应条件
1: 1,4-dioxane
2: HI
3: HCl,formaline
View Scheme
参考文献
Gmelin Handbook: F: PerFHalOrg.7, 1, page 1 - 84
参考文献
Gmelin Handbook: F: PerFHalOrg.8, 4, page 152 - 228
